New X-Men: E is for Extinction

The evolution of the X-Men begins here! Every day, the number of mutants on Earth grows exponentially, and the time has come for Homo superior to embrace its destiny. At the forefront stands Professor Charles Xavier and the X-Men. Now they face a deadly new threat with the emergence of Cassandra Nova, a truly diabolical foe who will change the fate of mutantkind forever! Collecting New X-Men #114-118 and New X-Men Annual #1